Hydroxyapatites: Key Structural Questions and Answers from Dynamic Nuclear Polarization

Phosphorus and survival: key questions that need answers.

Answers and Questions from the KvAP Structures

The recent landmark structures of KvAP, a voltage-gated potassium (Kv) channel, provide the first high-resolution experimental structural models of this class of proteins. Previous extensive studies of Kv channels provide a means to evaluate and interpret the KvAP structures. In this minireview, we survey different experimental approaches to Kv channels and map these findings to KvAP, showing t...

Conflating Answers: to and from Design Questions

Structural answers and persistent questions about how nicotinic receptors work.

The electron diffraction structure of nicotinic acetylcholine receptor (nAChR) from Torpedo marmorata and the X-ray crystallographic structure of acetylcholine binding protein (AChBP) are providing new answers to persistent questions about how nAChRs function as biophysical machines and as participants in cellular and systems physiology. New high-resolution information about nAChR structures mi...

Questions, Answers and Presuppositions

The paper deals with empirical questions that come attached with a presupposition. In case that the presupposition is not true, there is no unambiguous direct answer. In such a case an adequate complete answer is a negated presupposition. Yet these simple ideas are connected with a bunch of problems. First, we must distinguish between a pragmatic and semantic presupposition, and thus also betwe...